Currently, the only procedure for excess fat under the chin is surgical liposuction that we usually called it losing double chin. Now there is a research study for reducing excess fat under the chin. The study is evaluating the safety and effectiveness of an investigational, injectable medication, sodium deoxycholate ATX-101 to reduce the excess fat on the face.

Deoxycholate is a naturally occurring bile acid that solubilises dietary fat in humans and other animals, thereby aiding in its digestion. The clinical research study will include approximately 350 men and women between the ages of 18 and 65 who have excess fat under their chins.

Study volunteers must meet the following criteria:

Be age 18-65
Have excess fat under their chin
Have a stable body weight for at least 6 months

Other criteria must also be met to participate.

Participation in the study will last up to 32 weeks. During this time, participants visit the study site 11 times and will receive either placebo or investigational study medication. Placebos are an inactive substance that look like the investigational study medication and are used to make sure effects observed during a clinical research study are actually caused by the investigational study medication. There is a one in three chance of receiving the placebo.

Study participants will receive study related exams, lab tests and investigational study medication at no charge.

The following study sites are currently participating in this research study:
Wimpole Aesthetics Centre
48 Wimpole Street

Tel: 020 7224 2247


Medizen Clinic
Suite A, 1st Floor
Astor House
282 Lichfield Road Mere Green
Sutton Coldfield
West Midlands
B74 2UG

Tel: 0121 308 4373


The Laser and Light Cosmetic Medical Clinic
1 Church Gate Mews
LE11 1TZ

Tel: 01509 266882


Cellite Clinic
52 Charles Street
CF10 2GF

Tel: 02920 644644


Additional study site locations will be available in the coming weeks. Please revisit to get the most up-to-date information on the sites that are currently participating in the Double Chin Research study.

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